Case Report on Anti-Tubercular Drug Induced Hepatoxicity / Modified ATT

Authors: M Saru Khan, Basil Sunny, Rithuvaren M Krishnan

Indian Journal of Pharmacy Practice, Vol. 14, Issue 4, pp. 294-297, (2021)

DOI: 10.5530/ijopp.14.4.59

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Abstract

This case summary focusing on a 67-year male patient admitted in Sun rise Hospital, Kochi with k/c/o active tubercular on cat.2 ATT, now patient came complaint with c/o decreased appetite, food intake, nausea, vomiting and excessive fatigability. The patient was received first line anti tubercular drugs 6 months back RHZE (Rifampin, Pyrazinamide, Ethambutol, and Isoniazid) and discontinued medication 2 months back. Now it is developed a severe hepatitis which is an adverse drug reaction of the Antitubercular drugs.

Keywords: Hepatitis, Adverse drug reaction of anti-TB drug, Treatment, Pulmonary Koch infection, ALT, AST, Modified att.

IJOPP

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