A Case Report on Efavirenz Induced Gynaecomastia

Published on:November 2017
Indian Journal of Pharmacy Practice, 2017; 10(3):223-226
Case Report | doi:10.5530/ijopp.10.3.45


A Case Report on Efavirenz Induced Gynaecomastia


Authors and affiliation (s):

Rajalakshmi Rukmangathen1*, Vasundara Devi Brahmanapalli2, Meghana Devulapalli3, Durga Prasad Thammisetty4, Avanthi Bondalapati3, Shabana Banu Shaik3, Pavan Kumar Bathula3

1Patient Safety Pharmacovigilance Associate (Pharmacovigilance Programme of India), ADR Monitoring Centre (AMC), S.V. Medical College, Tirupathi, Andhra Pradesh, INDIA.

2Co-ordinator AMC, Professor & Head of the Department of Pharmacology, S. V. Medical College, Tirupathi, Andhra Pradesh, INDIA.

3Student, Doctor of Pharmacy, Department of Pharmacy Practice, Sri Padmavathi School of Pharmacy, Tiruchanoor, Andhra Pradesh, INDIA.

4Assistant Professor, Department of Pharmacy Practice, Sri Padmavathi School of Pharmacy, Tiruchanoor, Andhra Pradesh, INDIA.

Abstract:

Gynaecomastia in simple terms means development of breast in the males. This may be associated with various clinical conditions in men depending on the age at the time of diagnosis and may be due to intake of certain drugs that have the potential to cause breast enlargement. In HIV positive individuals Antiretro viral agent’s intake was associated with development of breast tissue in males with efavirenz being one of such drugs. We report a case of efavirenz induced gynaecomastia in 37 year old male seropositive patient.

Key words: Breast masses, Antiretroviral therapy, Drug induced gynaecomastia, Fine needle aspiration Hypothesis/ mechanisms of enlarged breast tissue, Seropositive, Breast enlargement, Efavirenz, Gynaecomastia.




 

The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

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